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Mini-informes de evidencia para preguntas hospitalarias — generados con inScope, nuestro motor de evidencia clínica, y revisados clínicamente antes de publicarse.

How fast can serum sodium be corrected safely in chronic hyponatremia?

In chronic hyponatremia, target a rise of 4–6 mEq/L in any 24-hour period and do not exceed 8 mEq/L per 24 hours in patients at high risk for osmotic demyelination syndrome (ODS). Many guidelines permit up to 10 mEq/L per 24 hours in low-risk patients, but 8 is the safer working ceiling in hospital practice.

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