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Clinical Guides

Evidence micro-briefs for inpatient questions — generated with inScope, our clinical evidence engine, and clinically reviewed before publication.

How fast can serum sodium be corrected safely in chronic hyponatremia?

In chronic hyponatremia, target a rise of 4–6 mEq/L in any 24-hour period and do not exceed 8 mEq/L per 24 hours in patients at high risk for osmotic demyelination syndrome (ODS). Many guidelines permit up to 10 mEq/L per 24 hours in low-risk patients, but 8 is the safer working ceiling in hospital practice.

Generated with inScopehyponatremiaelectrolytesODSinpatient